Hollywood couple Brad Pitt and Jennifer Aniston have announced that they have split up after what they describe as "much thoughtful consideration".
In a joint statement issued by Pitt's publicist, the two actors said they had decided to formally separate after seven years together.
Pitt, 41, and Aniston, 35, were seen as Hollywood's golden couple, with a solid marriage and successful careers.
They were married in a lavish ceremony at a Malibu estate in July 2000.
We ask in advance for your kindness and sensitivity in the coming months
Joint statement by Brad Pitt and Jennifer Aniston
The couple have no children. There is no indication whether they plan to file for divorce.
Their statement said: "For those who follow these sorts of things, we would like to explain that our separation is not the result of any speculation reported by the tabloid media - this decision is the result of much thoughtful consideration.
"We happily remain committed and caring friends with great love and admiration for one another.
"We ask in advance for your kindness and sensitivity in the coming months."
Tabloid speculation
The announcement of the split followed months of speculation in newspapers on both sides of the Atlantic, including reports that Pitt wanted to become a father but Aniston was reluctant to start a family.
A break-up was regarded as imminent after Aniston was spotted without her wedding ring in December, but the wedding band reappeared in later photographs.
Pitt and Aniston, shortly after their engagement was announced
Aniston's spokesman said the pair spent the New Year holidaying in the Caribbean with her former Friends co-star Courteney Cox and her husband, David Arquette.
The couple met on a dinner date in 1998. Pitt was already among Hollywood's leading men after critically acclaimed performances in the thriller Seven and Terry Gilliam's Twelve Monkeys.
Aniston was already a well-known face around the world for her role as the glamorous Rachel Green in the hit TV series Friends, which began in 1994 and ran for 10 years.
Prior to meeting Aniston, Pitt had dated Kalifornia co-star Juliette Lewis for several years and was engaged to his Seven co-star Gwyneth Paltrow for six months in 1997.
Marriage 'merger'
Pitt and Aniston dated for several years before marrying in a private ceremony in Malibu, California, in 2000.
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In 2001, Pitt called his marriage to Aniston a "merger".
"The thing with our marriage is that there was an opening in the Hollywood couple slot, and unfortunately we've fallen into it.
"Which I don't like very much...It doesn't leave us room to be human, to make our mistakes and have our struggles."
Pitt's recent roles have included well received performances in the thriller Fight Club in 1999 and playing a bareknuckle boxer in Guy Ritchie's Snatch (2000).